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Immuno Concepts was founded in 1979 with a commitment to develop state-of-the-art diagnostic assays for systemic rheumatic diseases.

Immuno Concepts not only pioneered the conversion from rodent tissue to HEp-2 cells for detection of anti-nuclear antibodies (ANAs), but also overcame one of the main pitfalls of ANA detection with the introduction of HEp-2000®, a patented ANA substrate genetically improved with increased sensitivity for detection of autoantibodies to SS-A/Ro. Over thirty worldwide publications meanwhile confirmed the clinically superior performance of HEp-2000®.